Michael Elftman

Dr. Elftman earned his B.S. in Microbiology from Michigan State University and his Ph.D. in Immunology and Infectious Disease from The Pennsylvania State University.  He joined the Department of Biomedical & Diagnostic Sciences in 2012 after completing postdoctoral training in mucosal immunology at the University of Michigan.  He currently teaches undergraduate and graduate-level immunology and microbiology.  His research interests include mucosal immunology and mechanisms of microbicidal activity.

Selected Publications

“A marked reduction in priming of cytotoxic CD8+ T cells mediated by stress-induced glucocorticoids involves multiple deficiencies in cross-presentation by dendritic cells.”  Hunzeker JT, Elftman MD, Mellinger JC, Princiotta MF, Bonneau RH, Truckenmiller ME, Norbury CC.  J Immunol. 2011 Jan 1;186(1):183-94.

“Stress-induced glucocorticoids at the earliest stages of herpes simplex virus-1 infection suppress subsequent antiviral immunity, implicating impaired dendritic cell function.”  Elftman MD, Hunzeker JT, Mellinger JC, Bonneau RH, Norbury CC, Truckenmiller ME.  J Immunol. 2010 Feb 15;184(4):1867-75.

“Corticosterone impairs dendritic cell maturation and function.”  Elftman MD, Norbury CC, Bonneau RH, Truckenmiller ME.  Immunology. 2007 Oct;122(2):279-90.

“Cytokine gene expression in peripheral blood mononuclear cells and tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis: evidence for an inherent proinflammatory gene expression pattern.”  Coussens PM, Verman N, Coussens MA, Elftman MD, McNulty AM.  Infect Immun. 2004 Mar;72(3):1409-22.

“Bovine mammary gene expression profiling using a cDNA microarray enhanced for mammary-specific transcripts.”  Suchyta SP, Sipkovsky S, Halgren RG, Kruska R, Elftman M, Weber-Nielsen M, Vandehaar MJ, Xiao L, Tempelman RJ, Coussens PM.  Physiol Genomics. 2003 Dec 16;16(1):8-18.

Research Interests

•    Microbicidal agents
•    Mucosal immunology
•    Psychoneuroimmunology