Dr. Elftman earned his BS in Microbiology from Michigan State University and his PhD in Immunology and Infectious Disease from The Pennsylvania State University. He joined the Department of Biomedical & Diagnostic Sciences in 2012 after completing postdoctoral training in mucosal immunology at the University of Michigan. He currently teaches undergraduate and graduate-level immunology and microbiology. His research interests include mucosal immunology and mechanisms of microbicidal activity.
“A marked reduction in priming of cytotoxic CD8+ T cells mediated by stress-induced glucocorticoids involves multiple deficiencies in cross-presentation by dendritic cells.” Hunzeker JT, Elftman MD, Mellinger JC, Princiotta MF, Bonneau RH, Truckenmiller ME, Norbury CC. J Immunol. 2011 Jan 1;186(1):183-94.
“Stress-induced glucocorticoids at the earliest stages of herpes simplex virus-1 infection suppress subsequent antiviral immunity, implicating impaired dendritic cell function.” Elftman MD, Hunzeker JT, Mellinger JC, Bonneau RH, Norbury CC, Truckenmiller ME. J Immunol. 2010 Feb 15;184(4):1867-75.
“Corticosterone impairs dendritic cell maturation and function.” Elftman MD, Norbury CC, Bonneau RH, Truckenmiller ME. Immunology. 2007 Oct;122(2):279-90.
“Cytokine gene expression in peripheral blood mononuclear cells and tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis: evidence for an inherent proinflammatory gene expression pattern.” Coussens PM, Verman N, Coussens MA, Elftman MD, McNulty AM. Infect Immun. 2004 Mar;72(3):1409-22.
“Bovine mammary gene expression profiling using a cDNA microarray enhanced for mammary-specific transcripts.” Suchyta SP, Sipkovsky S, Halgren RG, Kruska R, Elftman M, Weber-Nielsen M, Vandehaar MJ, Xiao L, Tempelman RJ, Coussens PM. Physiol Genomics. 2003 Dec 16;16(1):8-18.
• Microbicidal agents
• Mucosal immunology